Because Stage IV mesothelioma affects several parts of the body, patients may experience a variety of symptoms in various locations throughout the body. Two of the most common symptoms are severe chest pain and difficulty breathing. In some cases, tumors will spread to the esophagus and stomach, leading to a loss in appetite and difficulty swallowing. Abdominal pain can also be a symptom of Stage IV mesothelioma if the cancer has spread to the lower abdomen.
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